Publications by MIVAC researchers 2010

    1. Annerbrink K, Jönsson EG, Olsson M, Nilsson S, Sedvall GC, Anckarsäter H, Eriksson E. Associations between the angiotensin-converting enzyme insertion/deletion polymorphism and monoamine metabolite concentrations in cerebrospinal fluid. Psychiatry Res. 2010 May 16.  PubMed PMID: 20483169.
    2. Bartschat S, Samuelsson T. U12 type introns were lost at multiple occasions during evolution. BMC Genomics. 2010 Feb 11;11(1):106.
    3. Bhuiyan TR, Lundin SB, Khan AI, Lundgren A, Harris JB, Calderwood SB, Qadri F. Cholera caused by Vibrio cholerae O1 induces T-cell responses in the circulation. Infect Immun. 2009 May;77(5):1888-93. Epub 2009 Feb 23. PubMed PMID: 19237532; PubMed Central PMCID: PMC2681774.
    4. Bergqvist P, Stensson A, Lycke NY, Bemark M. T cell-independent IgA class switch recombination is restricted to the GALT and occurs prior to manifest germinal center formation. J Immunol. 2010 Apr 1;184(7):3545-53. Epub 2010 Mar 5. PubMed PMID: 20207993.
    5. Bäckhed F. 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: the normal gut microbiota in health and disease. Clin Exp Immunol. 2010 Apr;160(1):80-4. PubMed PMID: 20415855; PubMed Central PMCID: PMC2841839.
    6. Carén H, Kryh H, Nethander M, Sjöberg RM, Träger C, Nilsson S, Abrahamsson J, Kogner P, Martinsson T. High-risk neuroblastoma tumors with 11q-deletion display a poor prognostic, chromosome instability phenotype with later onset. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4323-8. Epub 2010 Feb 9. PubMed PMID: 20145112; PubMed Central PMCID: PMC2840092.
    7. Chowdhury F, Begum YA, Alam MM, Khan AI, Ahmed T, Bhuiyan MS, Harris JB, LaRocque RC, Faruque AS, Endtz H, Ryan ET, Cravioto A, Svennerholm AM, Calderwood SB, Qadri F. Concomitant enterotoxigenic Escherichia coli infection induces increased immune responses to Vibrio cholerae O1 antigens in patients with cholera in Bangladesh. Infect Immun. 2010 May;78(5):2117-24. Epub 2010 Feb 22. PubMed PMID: 20176796; PubMed Central PMCID: PMC2863502.
    8. Daborg J, von Otter M, Sjölander A, Nilsson S, Minthon L, Gustafson DR, Skoog I, Blennow K, Zetterberg H. Association of the RAGE G82S polymorphism with Alzheimer's disease. J Neural Transm. 2010 Jul;117(7):861-7. Epub 2010 Jun 22. PubMed PMID: 20567859; PubMed Central PMCID: PMC2895876.
    9. Darmoise A, Teneberg S, Bouzonville L, Brady RO, Beck M, Kaufmann SH, Winau F. Lysosomal alpha-Galactosidase Controls the Generation of Self Lipid Antigens for Natural Killer T Cells. Immunity. 2010 Aug 18.  PubMed PMID: 20727792.
    10. Dávila López M, Martínez Guerra JJ, Samuelsson T. Analysis of gene order conservation in eukaryotes identifies transcriptionally and functionally linked genes. PLoS One. 2010 May 14;5(5):e10654. PubMed PMID: 20498846; PubMed Central PMCID: PMC2871058.
    11. Del Campo J, Lindqvist M, Cuello M, Bäckström M, Cabrerra O, Persson J, Perez O, Harandi AM. Intranasal immunization with a proteoliposome-derived cochleate containing recombinant gD protein confers protective immunity against genital herpes in mice. Vaccine. 2010 Feb 3;28(5):1193-200. Epub 2009 Nov 27.
    12. Diswall M, Angström J, Karlsson H, Phelps CJ, Ayares D, Teneberg S, Breimer ME. Structural characterization of alpha1,3-galactosyltransferase knockout pig heart and kidney glycolipids and their reactivity with human and baboon antibodies. Xenotransplantation. 2010 Jan;17(1):48-60. PubMed PMID: 20149188.
    13. Edén A, Andersson LM, Andersson O, Flamholc L, Josephson F, Nilsson S, Ormaasen V, Svedhem V, Säll C, Sönnerborg A, Tunbäck P, Gisslén M. Differential effects of efavirenz, lopinavir/r, and atazanavir/r on the initial viral decay rate in treatment na√Øve HIV-1-infected patients. AIDS Res Hum Retroviruses. 2010  May;26(5):533-40. PubMed PMID: 20455766.
    14. Eigenbrot C, Ultsch M, Dubnovitsky A, Abrahmsén L, Härd T. Structural basis for high-affinity HER2 receptor binding by an engineered protein. Proc Natl Acad  Sci U S A. 2010 Aug 9.  PubMed PMID: 20696930.
    15. Fahlén-Yrlid L, Gustafsson T, Westlund J, Holmberg A, Strömbeck A, Blomquist  M, MacPherson GG, Holmgren J, Yrlid U. CD11c(high )dendritic cells are essential for activation of CD4+ T cells and generation of specific antibodies following mucosal immunization. J Immunol. 2009 Oct 15;183(8):5032-41. Epub 2009 Sep 28. PubMed PMID: 19786541.
    16. Fang Y, Larsson L, Mattsson J, Lycke N, Xiang Z. Mast Cells Contribute to the Mucosal Adjuvant Effect of CTA1-DD after IgG-Complex Formation. J Immunol. 2010 Sep 1;185(5):2935-41. Epub 2010 Jul 30. PubMed PMID: 20675596.
    17. Klingenberg R, Lebens M, Hermansson A, Fredrikson GN, Strodthoff D, Rudling M, Ketelhuth DF, Gerdes N, Holmgren J, Nilsson J, Hansson GK. Intranasal immunization with an apolipoprotein B-100 fusion protein induces antigen-specific regulatory T cells and reduces atherosclerosis. Arterioscler Thromb Vasc Biol. 2010 May;30(5):946-52. Epub 2010 Feb 18. PubMed PMID: 20167655.
    18. Hansson GC. Sparkling water--bicarbonate for cervix and cystic fibrosis. J Physiol. 2010 Aug 1;588(Pt 15):2685. PubMed PMID: 20675814.
    19. Harandi AM, Medaglini D, Shattock RJ; Working Group convened by EUROPRISE. Vaccine adjuvants: A priority for vaccine research. Vaccine. 2010 Jan 9.
    20. Hasselberg A, Ekman L, Yrlid LF, Schön K, Lycke NY. ADP-Ribosylation Controls  the Outcome of Tolerance or Enhanced Priming Following Mucosal Immunization. J Immunol. 2010 Feb 8.
    21. Jansson L, Angström J, Lebens M, Imberty A, Varrot A, Teneberg S. Carbohydrate binding specificities and crystal structure of the cholera toxin-like B-subunit from Citrobacter freundii. Biochimie. 2010 May;92(5):482-90. Epub 2010 Feb 18. PubMed PMID: 20171259.
    22. Jespers V, Harandi AM, Hinkula J, Medaglini D, Le Grand R, Stahl-Hennig C, Bogers W, El Habib R, Wegmann F, Fraser C, Cranage M, Shattock RJ, Spetz AL. Assessment of mucosal immunity to HIV-1. Expert Rev Vaccines. 2010 Apr;9(4):381-94. PubMed PMID: 20370549.
    23. Johansson ME, Holmén Larsson JM, Hansson GC. Microbes and Health Sackler Colloquium: The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions. Proc Natl Acad Sci U S A. 2010 Jun 25.  PubMed PMID: 20615996.
    24. Karlsson H, Halim A, Teneberg S. Differentiation of glycosphingolipid-derived glycan structural isomers by liquid chromatography/mass spectrometry. Glycobiology. 2010 Sep;20(9):1103-16. Epub 2010 May 12. PubMed PMID: 20466655.
    25. Klingenberg R, Lebens M, Hermansson A, Fredrikson GN, Strodthoff D, Rudling M, Ketelhuth DF, Gerdes N, Holmgren J, Nilsson J, Hansson GK. Intranasal Immunization With an Apolipoprotein B-100 Fusion Protein Induces Antigen-Specific Regulatory T Cells and Reduces Atherosclerosis. Arterioscler Thromb Vasc Biol. 2010 Feb 18.
    26. Koppisetty CA, Nasir W, Strino F, Rydell GE, Larson G, Nyholm PG. Computational studies on the interaction of ABO-active saccharides with the norovirus VA387 capsid protein can explain experimental binding data. J Comput Aided Mol Des. 2010 May;24(5):423-31. Epub 2010 Apr 21. PubMed PMID: 20407802.
    27. Lagergård T, Hadad R, Tunbäck P, Lindholm L, Löwhagen GB, Unemo M. Distribution of Chlamydia trachomatis ompA genovars and the new variant of C. trachomatis in the Göteborg area, Sweden. Eur J Clin Microbiol Infect Dis. 2010 May;29(5):609-11. Epub 2010 Mar 1. PubMed PMID: 20195670
    28. Lindén SK, Sheng YH, Every AL, Miles KM, Skoog EC, Florin TH, Sutton P, McGuckin MA. MUC1 limits Helicobacter pylori infection both by steric hindrance and by acting as a releasable decoy. PLoS Pathog. 2009 Oct;5(10):e1000617. Epub 2009 Oct 9. PubMed PMID: 19816567; PubMed Central PMCID: PMC2752161.
    29. Lindgren A, Pavlovic V, Flach CF, Sjöling A, Lundin S. Interferon-gamma secretion is induced in IL-12 stimulated human NK cells by recognition of Helicobacter pylori or TLR2 ligands. Innate Immun. 2010 Feb 3.
    30. Lindgren A, Yun CH, Lundgren A, Sjöling A, Ohman L, Svennerholm AM, Holmgren J, Lundin SB. CD8- natural killer cells are greatly enriched in the human gastrointestinal tract and have the capacity to respond to bacteria. J Innate Immun. 2010;2(3):294-302. Epub 2010 Feb 16. PubMed PMID: 20375553.
    31. Luheshi LM, Hoyer W, de Barros TP, van Dijk Härd I, Brorsson AC, Macao B, Persson C, Crowther DC, Lomas DA, Ståhl S, Dobson CM, Härd T. Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo. PLoS Biol. 2010 Mar 16;8(3):e1000334. PubMed PMID: 20305716; PubMed Central PMCID: PMC2838747.
    32. Lundqvist A, Fernandez-Rodrigues J, Ahlman K, Lagergård T. Detoxified Haemophilus ducreyi cytolethal distending toxin and induction of toxin specific antibodies in the genital tract. Vaccine. 2010 Aug 16;28(36):5768-73. Epub 2010 Jul 4. PubMed PMID: 20609397.
    33. Mejías-Luque R, Lindén SK, Garrido M, Tye H, Najdovska M, Jenkins BJ, Iglesias M, Ernst M, de Bolós C. Inflammation modulates the expression of the intestinal mucins MUC2 and MUC4 in gastric tumors. Oncogene. 2010 Mar 25;29(12):1753-62. Epub 2010 Jan 11. PubMed PMID: 20062084.
    34. Mitternacht S, Staneva I, Härd T, Irbäck A. Comparing the folding free-energy  landscapes of Abeta42 variants with different aggregation properties. Proteins. 2010 Sep;78(12):2600-8. PubMed PMID: 20589631.
    35. Muccioli GG, Naslain D, Bäckhed F, Reigstad CS, Lambert DM, Delzenne NM, Cani PD. The endocannabinoid system links gut microbiota to adipogenesis. Mol Syst Biol. 2010 Jul 27;6:392. PubMed PMID: 20664638.
    36. Nicklasson M, Klena J, Rodas C, Bourgeois AL, Torres O, Svennerholm AM, Sjoling A. Enterotoxigenic Escherichia coli multilocus sequence types in Guatemala and Mexico. Emerg Infect Dis. 2010 Jan;16(1):143-6. PubMed PMID: 20031063; PubMed Central PMCID: PMC2874370.
    37. Nilsson J, Nilsson J, Larson G, Grahn A. Characterization of site-specific O-glycan structures within the mucin-like domain of alpha-dystroglycan from human skeletal muscle. Glycobiology. 2010 Sep;20(9):1160-9. Epub 2010 May 27. PubMed PMID: 20507882.
    38. Png CW, Lindén SK, Gilshenan KS, Zoetendal EG, McSweeney CS, Sly LI, McGuckin MA, Florin TH. Mucolytic Bacteria With Increased Prevalence in IBD Mucosa Augment In Vitro Utilization of Mucin by Other Bacteria. Am J Gastroenterol. 2010 Jul 20.  PubMed PMID: 20648002.
    39. Raghavan S, Harandi AM. 'Help' from an unexpected source: Polyclonal Tregs enhance antibody response to mucosal immunization. Immunol Cell Biol. 2010 Jul 27.  PubMed PMID: 20661258.
    40. Raghavan S, Ostberg AK, Flach CF, Ekman A, Blomquist M, Czerkinsky C, Holmgren J. Sublingual immunization protects against Helicobacter pylori infection and induces T and B cell responses in the stomach. Infect Immun. 2010 Aug 9.  PubMed PMID: 20696831.
    41. Ruud J, Bäckhed F, Engblom D, Blomqvist A. Deletion of the gene encoding MyD88 protects from anorexia in a mouse tumor model. Brain Behav Immun. 2010 May;24(4):554-7. Epub 2010 Jan 18. PubMed PMID: 20093176.
    42. Rydström A, Wick MJ. Monocyte and neutrophil recruitment during oral Salmonella infection is driven by MyD88-derived chemokines. Eur J Immunol. 2009 Nov;39(11):3019-30. PubMed PMID: 19839009.
    43. Rydström A, Wick MJ. Salmonella inhibits monocyte differentiation into CD11chiMHC-IIhi cells in a MyD88-dependent fashion. J Leukoc Biol. 2010 Feb 2.  PubMed PMID: 20124491.
    44. Rydström A, Wick MJ. Salmonella inhibits monocyte differentiation into CD11c hi MHC-II hi cells in a MyD88-dependent fashion. J Leukoc Biol. 2010 May;87(5):823-32. PubMed PMID: 20124491.
    45. Sandberg A, Luheshi LM, Söllvander S, Pereira de Barros T, Macao B, Knowles TP, Biverstål H, Lendel C, Ekholm-Petterson F, Dubnovitsky A, Lannfelt L, Dobson CM, Härd T. Stabilization of neurotoxic Alzheimer amyloid-{beta} oligomers by protein engineering. Proc Natl Acad Sci U S A. 2010 Aug 16. [Epub ahead of print]PubMed PMID: 20713699.
    46. Sjöblom-Hallén A, Marklund U, Nerstedt A, Schön K, Ekman L, Bergqvist P, Löwenadler B, Lycke NY. Gene expression profiling identifies STAT3 as a novel pathway for immunomodulation by cholera toxin adjuvant. Mucosal Immunol. 2010 Jul;3(4):374-86. Epub 2010 Apr 7. PubMed PMID: 20375997.
    47. Spåhr H, Samuelsson T, Hällberg BM, Gustafsson CM. Structure of mitochondrial transcription termination factor 3 reveals a novel nucleic acid-binding domain. Biochem Biophys Res Commun. 2010 Jul 2;397(3):386-90. Epub 2010 Apr 27. PubMed PMID: 20430012.
    48. Sterky FH, Ruzzenente B, Gustafsson CM, Samuelsson T, Larsson NG. LRPPRC is a mitochondrial matrix protein that is conserved in metazoans. Biochem Biophys Res Commun. 2010 Aug 6;398(4):759-64. Epub 2010 Jul 13. PubMed PMID: 20633537.
    49. Tam MA, Wick MJ. MyD88 and interferon-alpha/beta are differentially required  for dendritic cell maturation but dispensable for development of protective memory against Listeria. Immunology. 2009 Nov;128(3):429-38. PubMed PMID: 20067542; PubMed Central PMCID: PMC2770690.
    50. Tengvall S, Lundgren A, Quiding-Järbrink M, Svennerholm AM. BAFF, stimulatory DNA and IL-15 stimulates IgA(+) memory B cells and provides a novel approach for analysis of memory responses to mucosal vaccines. Vaccine. 2010 Jul 26;28(33):5445-50. Epub 2010 Jun 12. PubMed PMID: 20547203.
    51. Thomsson KA, Bäckström M, Holmén Larsson JM, Hansson GC, Karlsson H. Enhanced Detection of Sialylated and Sulfated Glycans with Negative Ion Mode NanoliquidChromatography/Mass Spectrometry at High pH. Anal Chem. 2010 Feb 15;82(4):1470-7.
    52. Tobias J, Svennerholm AM, Holmgren J, Lebens M. Construction and expression of immunogenic hybrid enterotoxigenic Escherichia coli CFA/I and CS2 colonization fimbriae for use in vaccines. Appl Microbiol Biotechnol. 2010 Jul;87(4):1355-65. Epub 2010 Apr 20. PubMed PMID: 20405124.
    53. Tobias J, Holmgren J, Hellman M, Nygren E, Lebens M, Svennerholm AM. Over-expression of major colonization factors of enterotoxigenic Escherichia coli, alone or together, on non-toxigenic E. coli bacteria. Vaccine. 2010 Aug 19.  PubMed PMID: 20728524.
    54. Wada Y, Dell A, Haslam SM, Tissot B, Canis K, Azadi P, Bäckström M, CostelloCE, Hansson GC, Hiki Y, Ishihara M, Ito H, Kakehi K, Karlsson N, Hayes CE, Kato K, Kawasaki N, Khoo KH, Kobayashi K, Kolarich D, Kondo A, Lebrilla C, Nakano M, Narimatsu H, Novak J, Novotny MV, Ohno E, Packer NH, Palaima E, Renfrow MB, Tajiri M, Thomsson KA, Yagi H, Yu SY, Taniguchi N. Comparison of methods for profiling O-glycosylation: Human Proteome Organisation Human Disease Glycomics/Proteome Initiative multi-institutional study of IgA1. Mol CellProteomics. 2010 Apr;9(4):719-27. Epub 2009 Dec 28. PubMed PMID: 20038609; PubMed Central PMCID: PMC2860227.
    55. Waldenström J, Axelsson-Olsson D, Olsen B, Hasselquist D, Griekspoor P, Jansson L, Teneberg S, Svensson L, Ellström P. Campylobacter jejuni colonization in wild birds: results from an infection experiment. PLoS One. 2010 Feb 5;5(2):e9082. PubMed PMID: 20140204; PubMed Central PMCID: PMC2816703.
    56. Wermeling F, Lind SM, Jordö ED, Cardell SL, Karlsson MC. Invariant NKT cells limit activation of autoreactive CD1d-positive B cells. J Exp Med. 2010 May 10;207(5):943-52. Epub 2010 May 3. PubMed PMID: 20439539; PubMed Central PMCID: PMC2867286.
    57. Wesström J, Nilsson S, Sundström-Poromaa I, Ulfberg J. Health-related quality of life and restless legs syndrome among women in Sweden. Psychiatry Clin Neurosci. 2010 Aug 19.  PubMed PMID: 20727108.
    58. Velagapudi VR, Hezaveh R, Reigstad CS, Gopalacharyulu P, Yetukuri L, Islam S, Felin J, Perkins R, Borén J, Oresic M, Bäckhed F. The gut microbiota modulates host energy and lipid metabolism in mice. J Lipid Res. 2010 May;51(5):1101-12. Epub 2009 Dec 29. PubMed PMID: 20040631; PubMed Central PMCID: PMC2853437.
    59. Wising C, Magnusson M, Ahlman K, Lindholm L, Lagergård T. Toxic activity of the CdtB component of Haemophilus ducreyi cytolethal distending toxin expressed from an adenovirus 5 vector. APMIS. 2010 Feb;118(2):143-9. PubMed PMID: 20132178.
    60. von Otter M, Landgren S, Nilsson S, Celojevic D, Bergström P, Håkansson A, Nissbrandt H, Drozdzik M, Bialecka M, Kurzawski M, Blennow K, Nilsson M, Hammarsten O, Zetterberg H. Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease. BMC Med Genet. 2010 Mar 2;11:36. PubMed PMID: 20196834; PubMed Central PMCID: PMC2843602.
    61. von Otter M, Landgren S, Nilsson S, Zetterberg M, Celojevic D, Bergström P, Minthon L, Bogdanovic N, Andreasen N, Gustafson DR, Skoog I, Wallin A, Tasa G, Blennow K, Nilsson M, Hammarsten O, Zetterberg H. Nrf2-encoding NFE2L2 haplotypes influence disease progression but not risk in Alzheimer's disease and age-related cataract. Mech Ageing Dev. 2010 Feb;131(2):105-10. Epub 2010 Jan 12. PubMed PMID: 20064547.


    1. Bäckhed F, Crawford PA. Coordinated regulation of the metabolome and lipidome at the host-microbial interface. Biochim Biophys Acta. 2010 Mar;1801(3):240-5. Epub 2009 Sep 24. Review. PubMed PMID: 19782151; PubMed Central PMCID: PMC2823845.
    2. Harandi AM, Medaglini D. Mucosal adjuvants. Curr HIV Res. 2010 Jun;8(4):330-5. Review. PubMed PMID: 20353395.
    3. Mårtensson IL, Almqvist N, Grimsholm O, Bernardi AI. The pre-B cell receptor  checkpoint. FEBS Lett. 2010 Jun 18;584(12):2572-9. Epub 2010 Apr 24. Review. PubMed PMID: 20420836.
    4. Milling S, Yrlid U, Cerovic V, MacPherson G. Subsets of migrating intestinal  dendritic cells. Immunol Rev. 2010 Mar;234(1):259-67. Review. PubMed PMID: 20193024.
    5. Ohman L, Simrén M. Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions. Nat Rev Gastroenterol Hepatol. 2010 Mar;7(3):163-73. Epub 2010 Jan 26. Review. PubMed PMID: 20101257.
    6. Sun JB, Czerkinsky C, Holmgren J. Mucosally induced immunological tolerance,  regulatory T cells and the adjuvant effect by cholera toxin B subunit. Scand J Immunol. 2010 Jan;71(1):1-11. Review. PubMed PMID: 20017804.