Publications by MIVAC researchers 2008

  1. Ahmad, B. Kindlund, A. M. Svennerholm, and A. Lundgren. 2008. Comparison of mucosal B- and T-cell responses in Helicobacter pylori-infected subjects in a developing and a developed country. FEMS Immunology and Medical Microbiology 54:70-79.
  2. Ali, M., M. Emch, M. Yunus, D. Sack, A. L. Lopez, J. Holmgren, and J. Clemens. 2008. Vaccine Protection of Bangladeshi infants and young children against cholera: implications for vaccine deployment and person-to-person transmission. J  Ped Infect Dis 27:33-37.
  3. Belibasakis, G. N., M. Brage, T. Lagergard, and A. Johansson. 2008. Cytolethal distending toxin upregulates RANKL expression in Jurkat T-cells. Apmis 116:499-506.
  4. Benrick A, Jirholt P, Wernstedt I, Gustafsson M, Scheller J, Eriksson AL, Borén J, Hedner T, Ohlsson C, Härd T, Rose-John S, Jansson JO. A non-conservative polymorphism in the IL-6 signal transducer (IL6ST)/gp130 is associated with myocardial infarction in a hypertensive population. Regul Pept. 2008 Feb 7;146(1-3):189-96.
  5. Bergin, P. J., S. Raghavan, H. Svensson, S. Starckx, I. Van Aelst, I. Gjertsson, G. Opdenakker, and M. Quiding-Jarbrink. 2008. Gastric gelatinase B/matrix metalloproteinase-9 is rapidly increased in Helicobacter felis-induced gastritis. FEMS Immunol Med Microbiol 52:88-98.
  6. Berglund, M., J. A. Thomas, E. H. Hornquist, and O. H. Hultgren. 2008. Toll-like receptor cross-hyporesponsiveness is functional in interleukin-1-receptor-associated kinase-1 (IRAK-1)-deficient macrophages: differential role played by IRAK-1 in regulation of tumour necrosis factor and interleukin-10 production. Scand J Immunol 67:473-479.
  7. Bhuiyan, T. R., F. Qadri, P. K. Bardhan, M. M. Ahmad, B. Kindlund, A. M. Svennerholm, and A. Lundgren. 2008. Comparison of mucosal B- and T-cell responses in Helicobacter pylori-infected subjects in a developing and a developed country. FEMS Immunol Med Microbiol 54:70-79.
  8. Boraschi, D., M. Abebe Alemayehu, A. Aseffa, F. Chiodi, J. Chisi, G. Del Prete, T. M. Doherty, I. Elhassan, H. Engers, B. Gyan, A. M. Harandi, T. Kariuki, F. Kironde, B. Kouriba, J. Langhorne, T. Laskay, D. Medaglini, O. Olesen, P. Onyebujoh, C. Palma, R. Sauerwein, E. Sibanda, U. Steinhoff, A. Tagliabue, A. Thiel, M. Vahedi, and M. Troye-Blomberg. 2008. Immunity against HIV/AIDS, Malaria, and Tuberculosis during Co-Infections with Neglected Infectious Diseases: Recommendations for the European Union Research Priorities. PLoS Negl Trop Dis 2:e255.
  9. Brownlie, R. J., K. E. Lawlor, H. A. Niederer, A. J. Cutler, Z. Xiang, M. R. Clatworthy, R. A. Floto, D. R. Greaves, P. A. Lyons, and K. G. Smith. 2008. Distinct cell-specific control of autoimmunity and infection by FcgammaRIIb. J Exp Med 205:883-895.
  10. Eliasson, D. G., K. El Bakkouri, K. Schon, A. Ramne, E. Festjens, B. Lowenadler, W. Fiers, X. Saelens, and N. Lycke. 2008. CTA1-M2e-DD: a novel mucosal adjuvant targeted influenza vaccine. Vaccine 26:1243-1252.
  11. Dávila López M, Rosenblad MA, Samuelsson T. Computational screen for spliceosomal RNA genes aids in defining the phylogenetic distribution of major and minor spliceosomal components. Nucleic Acids Res. 2008 May;36(9):3001-10.
  12. Fjallbrant, H., M. Ridell, and L. O. Larsson. 2008. BCG scar and tuberculin reactivity in children and adults. Scand J Infect Dis 40:387-392.
  13. Franqueville, L., P. Henning, M. Magnusson, E. Vigne, G. Schoehn, M. E. Blair-Zajdel, N. Habib, L. Lindholm, G. E. Blair, S. S. Hong, and P. Boulanger. 2008. Protein crystals in Adenovirus type 5-infected cells: requirements for intranuclear crystallogenesis, structural and functional analysis. PLoS ONE 3:e2894.
  14. Fredin, M. F., L. Hultin, G. Hyberg, E. Rehnstrom, E. Hultgren Hornquist, S. Melgar, and L. Jansson. 2008. Predicting and monitoring colitis development in mice by micro-computed tomography. Inflamm Bowel Dis 14:491-499.
  15. Fritsch Fredin, M., A. Vidal, H. Utkovic, Y. Y. Gotlind, R. Willen, L. Jansson, E. Hultgren Hornquist, and S. Melgar. 2008. The application and relevance of ex vivo culture systems for assessment of IBD treatment in murine models of colitis. Pharmacol Res 58:222-231.
  16. He L, Sun Y, Takemoto M, Norlin J, Tryggvason K, Samuelsson T, Betsholtz C. The glomerular transcriptome and a predicted protein-protein interaction network. J Am Soc Nephrol. 2008 Feb;19(2):260-8.
  17. Gorander, S., T. Lagergard, M. Romanik, R. P. Viscidi, G. Martirosian, and J. A. Liljeqvist. 2008. Seroprevalences of herpes simplex virus type 2, five oncogenic human papillomaviruses, and Chlamydia trachomatis in Katowice, Poland. Clin Vaccine Immunol 15:675-680.
  18. Grdic.,  D., EL Bakkouri,  K. Schön,  K. A. Ramne, E. Festjens, B. Lowenadler, W. Fiers, X. Saelens, and N. Lycke. 2008. Adjuvant targeted CTA1-M2e-DD; a novel concept for mucosal delivery of a universal influenza A vaccine. Vaccine 26:1243-1252.
  19. Guy JE, Wigren E, Svärd M, Härd T, Lindqvist Y. New insights into multiple coagulation factor deficiency from the solution structure of human MCFD2. J Mol Biol. 2008 Sep 12;381(4):941-55.
  20. Hansson, M., M. Hermansson, H. Svensson, A. Elfvin, L. E. Hansson, E. Johnsson, A. Sjoling, and M. Quiding-Jarbrink. 2008. CCL28 is increased in human Helicobacter pylori-induced gastritis and mediates recruitment of gastric immunoglobulin A-secreting cells. Infect Immun 76:3304-3311.
  21. Harris, A. M., F. Chowdhury, Y. A. Begum, A. I. Khan, A. S. Faruque, A. M. Svennerholm, J. B. Harris, E. T. Ryan, A. Cravioto, S. B. Calderwood, and F. Qadri. 2008. Shifting prevalence of major diarrheal pathogens in patients seeking hospital care during floods in 1998, 2004, and 2007 in Dhaka, Bangladesh. Am J Trop Med 79:708-714.
  22. Hoyer W, Grönwall C, Jonsson A, Ståhl S, Härd T. Stabilization of a beta-hairpin in monomeric Alzheimer's amyloid-beta peptide inhibits amyloid formation. Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5099-104. Epub 2008 Mar 28.
  23. Hoyer W, Härd T. Interaction of Alzheimer's A beta peptide with an engineered binding protein--thermodynamics and kinetics of coupled folding-binding. J Mol Biol. 2008 Apr 25;378(2):398-411.
  24. Johansson DG, Macao B, Sandberg A, Härd T. SEA domain autoproteolysis accelerated by conformational strain: mechanistic aspects. J Mol Biol. 2008 Apr 4;377(4):1130-43.
  25. Johansson ME, Phillipson M, Petersson J, Velcich A, Holm L, Hansson GC. The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15064-9.
  26. Karlberg, M., Z. Xiang, and G. Nilsson. 2008. Fc gamma RI-mediated activation of human mast cells promotes survival and induction of the pro-survival gene Bfl-1. J  Clin Immunol 28:250-255.
  27. Lidell ME, Bara J, Hansson GC. Mapping of the 45M1 epitope to the C-terminal cysteine-rich part of the human MUC5AC mucin. FEBS J. 2008 Feb;275(3):481-9.
  28. Lidqvist, M., O. Nilsson, J. Holmgren, C. Hall, and C. Fermer. 2008. Phage display for site-specific immunization and characterization of high-risk human papillomavirus specific E7 monoclonal antibodies.
    J Immunol Methods 337:88-96.
  29. Lindén SK, Florin TH, McGuckin MA. Mucin dynamics in intestinal bacterial infection. PLoS One. 2008;3(12):e3952.
  30. Lindén SK, Bierne H, Sabet C, Png CW, Florin TH, McGuckin MA, Cossart P. Listeria monocytogenes internalins bind to the human intestinal mucin MUC2. Arch Microbiol. 2008 Jul;190(1):101-4.
  31. Lindén SK, Wickström C, Lindell G, Gilshenan K, Carlstedt I. Four modes of adhesion are used during Helicobacter pylori binding to human mucins in the oral and gastric niches. Helicobacter. 2008 Apr;13(2):81-93.
  32. Lindén S, Mahdavi J, Semino-Mora C, Olsen C, Carlstedt I, Borén T, Dubois A. Role of ABO secretor status in mucosal innate immunity and H. pylori infection. PLoS Pathog. 2008 Jan;4(1):e2.
  33. Lothigius, A., A. Janzon, Y. Begum, A. Sjoling, F. Qadri, A. M. Svennerholm, and I. Bolin. 2008. Enterotoxigenic Escherichia coli is detectable in water samples from an endemic area by real-time PCR. J Appl Microbiol 104:1128-1136.
  34. Lu, Y. J., J. Gross, D. Bogaert, A. Finn, L. Bagrade, Q. Zhang, J. K. Kolls, A. Srivastava, A. Lundgren, S. Forte, C. M. Thompson, K. F. Harney, P. W. Anderson, M. Lipsitch, and R. Malley. 2008. Interleukin-17A mediates acquired immunity to pneumococcal colonization. PLoS Pathog 4:e1000159.
  35. Macao B, Hoyer W, Sandberg A, Brorsson AC, Dobson CM, Härd T. Recombinant amyloid beta-peptide production by coexpression with an affibody ligand. BMC Biotechnol. 2008 Oct 30;8:82.
  36. Mahalanabis, D., A. L. Lopez, D. Sur, J. Deen, B. Manna, S. Kanungo, L. von Seidlein, R. Carbis, S. H. Han, S. H. Shin, S. Attridge, R. Rao, J. Holmgren, J. Clemens, and S. K. Bhattacharya. 2008. A randomized, placebo-controlled trial of the bivalent killed, whole-cell, oral cholera vaccine in adults and children in a cholera endemic area in Kolkata, India. PLoS ONE 3:e2323.
  37. Malmberg P, C. Kriegeskotte, HF. Arlinghaus, B . Hagenhoff, J. Holmgren, M. Nilsson and H .Nygren. 2008. Depth profiling of cells and tissues by using C60+ and SF5+ as sputter ions. Applied Surface Science 255: 926-928.
  38. Malmberg EK, Pelaseyed T, Petersson AC, Seidler UE, De Jonge H, Riordan JR, Hansson GC. The C-terminus of the transmembrane mucin MUC17 binds to the scaffold protein PDZK1 that stably localizes it to the enterocyte apical membrane in the small intestine. Biochem J. 2008 Mar 1;410(2):283-9.
  39. Nicklasson, M., A. Sjoling, M. Lebens, J. Tobias, A. Janzon, L. Brive, and A. M. Svennerholm. 2008. Mutations in the periplasmic chaperone leading to loss of surface expression of the colonization factor CS6 in enterotoxigenic Escherichia coli (ETEC) clinical isolates. Microb Pathogen 44:246-254.
  40. Nowroozalizadeh, S., M. Jansson, J. Adamsson, M. Lindblad, E. M. Fenyo, J. Holmgren, and A. M. Harandi. 2008. Suppression of HIV replication in vitro by CpG and CpG conjugated to the non toxic B subunit of cholera toxin. Current HIV Res 6:230-238.
  41. Nygren, E., J. Holmgren, and S. R. Attridge. 2008. Murine antibody responses following systemic or mucosal immunization with viable or inactivated Vibrio cholerae. Vaccine 26:6784-6790.
  42. Nystrom-Asklin, J., J. Adamsson, and A. M. Harandi. 2008. The adjuvant effect of CpG oligodeoxynucleotide linked to the non-toxic B subunit of cholera toxin for induction of immunity against H. pylori in mice. Scand J Immunol 67:431-440.
  43. Phillipson M, Johansson ME, Henriksnäs J, Petersson J, Gendler SJ, Sandler S, Persson AE, Hansson GC, Holm L. The gastric mucus layers: constituents and regulation of accumulation. Am J Physiol Gastrointest Liver Physiol. 2008 Oct;295(4):G806-12.
  44. Rolf, J., E. Berntman, M. Stenstrom, E. M. Smith, R. Mansson, H. Stenstad, T. Yamagata, W. Agace, M. Sigvardsson, and S. Cardell. 2008. Molecular profiling reveals distinct functional attributes of CD1d-restricted natural killer (NK) T cell subsets. Molecular Immunol 45:2607-2620.
  45. Sanchez J., and J.  Holmgren. 2008. Cholera toxin structure, gene regulation and pathophysiological and immunological aspects. Cell Mol Life Sci 65:1347-1360.
  46. Sun, J. B., C. F. Flach, C. Czerkinsky, and J. Holmgren. 2008. B lymphocytes promote expansion of regulatory T cells in oral tolerance: powerful induction by antigen coupled to cholera toxin B subunit. J Immunol 181:8278-8287.
  47. Sundling, C., K. Schon, A. Morner, M. N. Forsell, R. T. Wyatt, R. Thorstensson, G. B. Karlsson Hedestam, and N. Lycke. 2008. CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization. J Gen Virol 89:2954-2964.
  48. Sundstrom, P., S. B. Lundin, L. A. Nilsson, and M. Quiding Jarbrink. 2008. Human IgA-secreting cells induced by intestinal, but not systemic, immunization respond to CCL25 (TECK) and CCL28 (MEC). Eur J Immunol 38:3327-3338.
  49. Svennerholm, A.M., and I. Bolin. 2008. Enterotoxigenic Escherichia coli is detectable in water samples from an endemic area by real-time PCR. J Appl Microbiol 104:1128-1136.
  50. Syed ZA, Härd T, Uv A, van Dijk-Härd IF. A potential role for Drosophila mucins in development and physiology. PLoS One. 2008 Aug 22;3(8):e3041.
  51. Tam, M. A., M. Sundquist, and M. J. Wick. 2008. MyD88 and IFN-alphabeta differentially control maturation of bystander but not Salmonella-associated dendritic cells or CD11cintCD11b+ cells during infection. Cell Microbiol 10:1517-1529.
  52. Tengvall, S., D. O'Hagan, and A. M. Harandi. 2008. Rectal immunization generates protective immunity in the female genital tract against herpes simplex virus type 2 infection: relative importance of myeloid differentiation factor 88. Antiviral Res 78:202-214.
  53. Tengvall, S., and A. M. Harandi. 2008. Importance of myeloid differentiation factor 88 in innate and acquired immune protection against genital herpes infection in mice. J Reprod Immunol 78:49-57.
  54. Tobias, J., M. Lebens, I. Bolin, G. Wiklund, and A. M. Svennerholm. 2008. Construction of non-toxic Escherichia coli and Vibrio cholerae strains expressing high and immunogenic levels of enterotoxigenic E. coli colonization factor I fimbriae. Vaccine 26:743-752.
  55. Tobias, J., M. Lebens, S. Kallgard, M. Nicklasson, and A. M. Svennerholm. 2008. Role of different genes in the CS6 operon for surface expression of Enterotoxigenic Escherichia coli colonization factor CS6. Vaccine 26:5373-5380.
  56. Tobias, J., K. Andersson, A. Bialik, and D. Cohen. 2008. Preexisting antibodies to homologous colonization factors and heat-labile toxin in serum, and the risk to develop enterotoxigenic Escherichia coli-associated diarrhea. Diagn Microbiol Infect Dis 60:229-231.
  57. Zander, L., and M. Bemark. 2008. Identification of genes deregulated during serum-free medium adaptation of a Burkitt's lymphoma cell line. Cell Proliferation 41:136-155.


  58. Holmgren J. and JD. Clemens. 2008. Cholera immunity and cholera vaccination. In: Immunity against pathogens.  Vajdy M (Ed.), Springer Science, 173-194.
  59. Kadri, N., M. Blomquist, and S. Cardell. 2008. Type II natural killer
    T cells: a new target for immunomodulation? Expert Rev Clin Immunol 4:615-627.
  60. Lokmic, Z., T. Lammermann, M. Sixt, S. Cardell, R. Hallmann, and L. Sorokin. 2008. The extracellular matrix of the spleen as a potential organizer of immune cell compartments. Semin  Immunol  20:4-13.
  61. Marks, E. and Lycke, N.2008. Immunity Against Chlamydia trachomatis
    Immunity Against Mucosal Pathogens.
  62. Perez, O., and A. M. Harandi. 2008. 4th International Workshop in Vaccine Adjuvants and Parasitic Vaccines (adjuvant 2008). Expert Rev Vaccine 7:1151-1153.
  63. Sack D, Qadri F., and A.M. Svennerholm. 2008. Determinants of Responses to Oral vaccines in Developing Countries. Ann Nestlé (Engl) 66:71-79.
  64. Sun J.-B., Czerkinsky C.,. Holmgren J. 2008. Mucosally induced immunological tolerance: Strong potentiation by use of antigens coupled to cholera toxin B subunit. Int J Medical Biological Frontiers, in press.
  65. Svennerholm, A. M., and J. Tobias. 2008. Vaccines against enterotoxigenic Escherichia coli. Expert Rev Vaccine 7:795-804.
  66. Svennerholm, A.M. and F. Qadri. 2008. Mucosal immune responses against enterotoxigenic Escherichia coli (ETEC) in humans. In Immunity against Mucosal pathogens (M Vajdy,   ed), Chapter 6, Springer Verlag, pp 153-171.
  67. Tam, M. A., A. Rydstrom, M. Sundquist, and M. J. Wick. 2008. Early cellular responses to Salmonella infection: dendritic cells, monocytes, and more. Immunological Reviews 225:140-162.